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Histopathological changes in albino mouse testis induced by the administration of Tityus n. sp. venom J. Venom. Anim. Toxins
PENNA-VIDEAÚ,S.; CERMEÑO-VIVAS,J.; MORENO-MARVAL,M.; QUIROGA-NOTTI,M..
Scorpion envenoming is a public health concern in northeastern Venezuela. Specimens of the genus Tityus are responsible for most of these. In experimental animals, Tityus venom produces histopathological changes in the skeletal muscle and pancreas, but its toxicity to the reproductive system has not been studied. The aim of this work is to describe the histopathological changes in testis and epididymis of albino mice induced by the administration of Tityus n. sp. venom. Sub-lethal doses of venom (3.75 mg/g mouse) were administered intramuscularly (IM) daily for 4 days. On the fifth day, the animals were sacrificed and the testes and epididymes were quickly removed and processed for light microscopy. The venom induced alterations in spermatogenesis. Sertoli...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Testis; Sertoli cell; Epididymis; Scorpion; Venom; Mouse; Histopathology.
Ano: 2000 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79302000000200003
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Morphometric evaluation of the spermatogenesis in trahira Hoplias malabaricus (Bloch) (Characiformes, Erythrinidae) Zoologia
Bizzott,Paula M.; Godinho,Hugo P..
The Erythrinidae trahira, Hoplias malabaricus (Bloch, 1794), is widespread throughout South America river basins. We determined Sertoli cell supporting capacity (ratio of primary spermatocytes: Sertoli cells and spermatids: Sertoli cells), meiotic index (ratio of spermatids: primary spermatocytes) and the number of spermatogonial mitotic generations of this fish. The fish were captured in the Igarapava reservoir, Grande River, Alto Paraná River basin, Brazil. Testis fragments of three sexually mature trahiras were fixed in 5% buffered glutaraldehyde solution and embedded in glycol methacrylate. Serial sections of 2 and 3 µm in thickness were stained with 0.5% toluidine blue. Histological counts from cysts of primary spermatocytes and spermatids revealed,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Sertoli cell; Spermatogonial generations; Teleost testis morphometry.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-81752007000300003
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Propylthiouracil-induced hypothyroidism delays apoptosis during the first wave of spermatogenesis Biol. Res.
Silva,Doris; Lizama,Carlos; Tapia,Verónica; Moreno,Ricardo D.
Mammalian germ cell apoptosis plays a key role in controlling the correct number of germ cells supported by Sertoli cells during the first wave of spermatogenesis in mammalian puberty. However, little is known about hormonal factors that could influence the rate of germ cell apoptosis during puberty or adulthood. In this work we evaluate germ cell apoptosis under hypothyroidism induced by goitrogen propylthiouracil (PTU) during the first wave of spermatogenesis. Neonatally administered PTU promoted a delay in the differentiation of Sertoli cells as evaluated by the expression of clusterin using immunohistochemistry and RT-PCR. Clusterin had different expression levels in control and PTU-treated animals, but under both conditions the highest levels were...
Tipo: Journal article Palavras-chave: Testis; Spermatocyte; Sertoli cell; Caspase; Apoptosis; Thyroid.
Ano: 2011 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602011000200010
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Testis evaluation of adult Wistar rats after neonatal treatment with fluoxetine - doi: 10.4025/actascibiolsci.v35i1.10946 Biological Sciences
Silva Junior, Valdemiro Amaro da; Universidade Federal Rural de Pernambuco; Monteiro Filho, Waldo Oliveira; Universidade Federal Rural de Pernambuco; Pinto, Catarina Ferreira; Universidade Federal Rural de Pernambuco; Torres, Sandra Maria de; Universidade Federal Rural de Pernambuco; Tenorio, Bruno Mendes; Universidade Federal Rural de Pernambuco.
In current assay the serotoninergic system in newly-born Wistar rats underwent pharmacological modification by fluoxetine, a selective serotonin reuptake inhibitor (SSRI), to investigate its repercussion on testicular parameters in adult animals. Thirty animals were distributed according to treatment: control animals (n = 6), animals treated with 1 mg kg-1 (n = 6), 5 mg kg-1 (n = 6), 10 mg kg-1 (n = 6) and 20 mg kg-1 (n = 6) of fluoxetine (IP). When 150 days old, the animals were anesthetized and perfused intra-cardiacally with fixative solution. Testes were routinely processed for inclusion in plastic resin (methacrylate glycol). Further, 4 µm-thick histological sections were stained with toluidine blue/sodium borate 1% and analyzed histometrically....
Palavras-chave: 2.06.00.00-3 spermatogenesis; Sertoli cell; Sperm production; Fluoxetine chlorohydrate Morfologia.
Ano: 2012 URL: http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/10946
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The effects of Tynnanthus fasciculatus (Bignoniaceae) infusion on testicular parenchyma of adult Wistar rats Biol. Res.
Melo,Fabiana C. S. A; Matta,Sérgio L. P; Paula,Tarcízio A. R; Gomes,Marcos L. M; Oliveira,Luciana C.
Traditional medicine provides strong guidance for scientific experiments involving plant products used by the Brazilian people. The species "cipó-cravo" (Tynnanthus fasciculatus) is a plant commonly used either to combat indigestion and stomachaches, or as a general stimulant and aphrodisiac. In this study, the effects of "cipó-cravo" infusion were investigated within the testicular parenchyma of adult Wistar rats. Rats were divided into 3 groups: a control (distilled water) and two treated groups, which received the plant infusion (100 and 200mg/animal/day). The 200mg dose promoted a significant increase of the testicular parenchyma weight and of the volume and total length of the seminiferous tubules, as well as in total daily sperm production and sperm...
Tipo: Journal article Palavras-chave: Germ cell; Sertoli cell; Sperm production; Spermatogenesis.
Ano: 2010 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602010000400009
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